ABSTRACT
Ebola virus (EBV) is a deadly virus that has resulted in a number of deaths during its outbreaks in Africa in 2014–2016 and 2018–2019. This virus causes a hemorrhagic fever like other pathogenic viruses of the Filoviridae family with high mortality rate. The Ebola virus disease (EVD) occurred in a small town near the ebola river from which it intakes its name. EVD first found in 1976 in simultaneous out breaks one is Nzara South Sudan and second one is yambuku, DRC.It can be spared to the population via wild animals and after then if a healthy individual come in contact with ebola infected person so then healthy one is also infected and this cycle runs without precaution so that a large number of population get infected. Ebola virus (EBV) belongs to the Filoviridae family and it is specialized hemorrhagic fever and it is rare but fatal illness in human. According to world health organization average rate of fatality is about 50% cases and it varied from past outbreak from 25% to 90%. This particular virus humiliate a lot cells primarily it attacks on macrophages and dendritic cells and after that primary immune system start attacking against virus by using of cytokines a lots of cytokines attacks on virus at that time it look like whirlwind, But Filoviridae family particularly lethal because it affect wide range if organs. Ebola virus can affect spleen lung and kidneys and this particular virus affect cells of these organs those cells who are helping for chemical balance and some protein which is responsible for blood clotting.EVD can be rule out if preventive community get engagement. In community must have case namely management, infection prevention, control practices patient surveillance and good laboratory practice.
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